Chemical genomics and proteomics

reviews and protocols by Edward D. Zanders

Publisher: Humana Press in New York, N.Y

Written in English
Cover of: Chemical genomics and proteomics | Edward D. Zanders
Published: Pages: 243 Downloads: 770
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Subjects:

  • Genomics,
  • Methods,
  • Combinatorial chemistry,
  • Proteomics,
  • DNA microarrays,
  • Pharmacogenetics,
  • Biochemical genetics,
  • Laboratory Manuals,
  • Small Molecule Libraries

Edition Notes

Includes bibliographical references and index.

Statementedited by Edward D. Zanders
SeriesMethods in molecular biology -- 800, Springer protocols, Springer protocols, Methods in molecular biology (Clifton, N.J.) -- 800.
Classifications
LC ClassificationsQH447 .C47 2012
The Physical Object
Paginationxi, 243 p. :
Number of Pages243
ID Numbers
Open LibraryOL25246513M
ISBN 101617793485
ISBN 109781617793486, 9781617793493
LC Control Number2011937229
OCLC/WorldCa763308152

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Genomics and Proteomics | Boundless Biology. Since the publication of the pioneering first edition of Chemical Genomics and Proteomics more than seven years ago, the area of chemical genomics has rapidly expanded and diversified to numerous novel methods and subdisciplines, such as chemical glycomics Format: Hardcover.

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In Chemical Genomics and Proteomics: Reviews and Protocols, experts in the field present updated reviews of the chemistry of small molecules and their interaction with protein targets as well as. Since the publication of the pioneering first edition of Chemical Genomics and Proteomics more than seven years ago, the area of chemical genomics has rapidly expanded and diversified to numerous novel methods and subdisciplines, such as chemical glycomics.

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Genomics and proteomics approaches could be used to direct drug development processes by unearthing pathways involved in disease pathogenesis where intervention may be most successful. This book describes the basics of genomics and proteomics and highlights the various chemical.

In Chemical Genomics: Reviews and Protocols, leading edge researchers introduce the uninitiated into the various "flavors" of chemical genomics and describe a series of readily reproducible techniques for.

Abstract: The final product of gene expression is protein. Proteins are the functional entities of cells. The total number of proteins expressed in a cell is called a proteome. This chapter describes the.

From chemical genetics to chemical genomics. To move the somewhat ad hoc field of chemical genetics to a genome-wide scale requires approaches that are general.

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Chemical genomics technology has been steadily improving, delivering new biological probes and drugs, and the explicit use of the term 'chemical proteomics' has increased with it, as proteins have always been at the heart of this technology. In Chemical Genomics and Proteomics.

Utilizing small molecules in chemical genomics: Toward high-throughput (HT) approaches / Ferenc Darvas --Development and application of novel analytical methods in lipidomics / William J.

Griffiths --From chemical genomics to chemical proteomics. In this book, different genomics and proteomics technologies and principles are examined. The fundamental knowledge presented in this book opens up an entirely new way of approaching DNA chip technology, DNA array assembly, gene expression analysis, assessing changes in genomic DNA, structure-based functional genomics.

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Genomics and Proteomics, the two topics of this issue of Chemical Reviews, are deeply connected with each other at various many obvious links, both are technology-driven fields in Cited by: 8.

d) Label the proteins with a chemical tag Question 4 If your quantitative proteomics experiment contains a large number of samples, which of these would be a good method to chose. Chemical Genomics will be valuable to researchers, professionals, and students in many fields besides chemical genomics, including biology, biomedicine, chemistry and drug discovery.

Contents. Part I. Since the publication of the pioneering first edition of Chemical Genomics and Proteomics more than seven years ago, the area of chemical genomics has rapidly expanded and diversified to numerous.

Advances in chemistry, biology and genomics coupled with laboratory automation and computational technologies have led to the rapid emergence of the multidisciplinary field of chemical genomics.

Proteomics complements genomics and is useful when scientists want to test their hypotheses that were based on genes. Even though all cells of a multicellular organism have the same set of genes.

Chemogenomics, or chemical genomics, is the systematic screening of targeted chemical libraries of small molecules against individual drug target families (e.g., GPCRs, nuclear receptors, kinases. This volume in the Methods in Molecular Biology (TM) series presents updated reviews of the chemistry of small molecules and their interaction with protein targets as well as detailed protocols that cover.

Genomics and proteomics are changing our understanding of biology. To date, the greatest impact has come from DNA sequencing projects, which recently culminated in the unveiling of the near.

Proteomics was thought to be a natural extension after the field of genomics has deposited significant amount of data.

However, simply taking a straight verbatim approach to catalog all proteins in all tissues of different organisms is not viable. Researchers may need to focus on the perspectives of proteomics that are essential to the functional outcome of the cells.

In Integrative Proteomics. Molecular Omics publishes high-quality research in the -omics sciences. We welcome scientific research based on the application of any -omics technology and we encourage multi-omics approaches to solving important chemical or biological problems.

This includes combining different types of omics platforms encompassing genomics. The study of the function of proteomes is called proteomics. A proteome is the entire set of proteins produced by a cell type. Genomics led to proteomics (via transcriptomics) as a logical step.

.genomics. Genomics can give a rough estimation of expression of a protein. M ost of the proteins function in collaboration with other proteins, and the main goal of proteomics are to identify which proteins interact.

After genomics, proteomics. We introduce a new representation and feature extraction method for biological sequences. Named bio-vectors (BioVec) to refer to biological sequences in general with protein-vectors (ProtVec) for proteins (amino-acid sequences) and gene-vectors (GeneVec) for gene sequences, this representation can be widely used in applications of deep learning in proteomics and genomics.